Real Betis head coach Manuel Pellegrini may already have his starting XI picked but the Chilean will also be thinking about how the Spanish side can keep Bruno Fernandes quiet and how they will aim to get past Casemiro.
Without Luiz Felipe, Germán Pezzella will lead the defence on Thursday evening. Guido Rodríguez and William Carvalho will likely start as the double pivot and Sergio Canales could play in front of them, having recovered from injury.
Betis need goals after losing 4-1 to United at Old Trafford and striker Borja Iglesias should lead the line in Seville.
Possible Real Betis XI vs Manchester United
AS have predicted the following Betis XI:
Rui Silva – Ruibal, Pezzella, Edgar, Miranda – Guido, William – Canales, Ayoze, Juanmi – Borja Iglesias.
Kieran Quaile | GSFN
