Real Betis travel to Finland to face HJK Helsinki at the Bolt Stadium in their first Europa League game of the season. Kick-off is scheduled for 7.45pm local time (6.45pm CEST).
It is believed that Manuel Pellegrini will rotate his squad around to give some of his key players a rest before their big game against Villarreal on Sunday.
Willian José is expected to start instead of Borja Iglesias, while Juan Miranda will most likely be given the nod ahead of Álex Moreno.
Nabil Fekir is yet to recover from a muscle injury that he suffered against Real Madrid, giving veteran Joaquín the opportunity to make the starting XI for the first time this season.
Estadio Deportivo expect Pellegrini to field the following starting XI: Claudio Bravo – Youssouf Sabaly or Aitor Ruibal, Luiz Felipe or Germán Pezzella, Víctor Ruiz, Juan Miranda – Paul Akouokou , William Carvalho or Andrés Guardado – Luiz Henrique, Joaquín, Rodri – Willian José.